KARLSTAEDT LAB

Cardio-Oncology * Metabolism

Publications

Selection of important scientific publication

2021

  1. Karlstaedt A, Barrett M, Hu R, Gammons ST, Ky B. “Cardio-Oncology - Understanding the Intersections between Cardiac Metabolism and Cancer Biology.” JACC: Basic to Translational Science, 2021

2020 - 2016

  1. Aksentijevic D, Karlstaedt A et al. “Intracellular sodium elevation reprograms cardiac metabolism.” Nature Communications, 2020

  2. Karlstaedt A, Khanna R, Thangam M, Taegtmeyer H. Glucose 6-phosphate acts as a metabolic signal via phosphoglucose isomerase in heart muscle. Circ. Res. 2020

  3. Karlstaedt A, Schiffer W, Taegtmeyer H Actionable metabolic pathways in heart failure and cancer-Lessons from cancer cell metabolism. Front Cardiovasc Med. 2018

  4. Taegtmeyer H, Karlstaedt A, Rees ML, Davogustto G. Oncometabolic Tracks in the Heart. Circ Res. 2017

  5. Karlstaedt A, Zhang X, Vitrac H, Harmancey R, Vasquez H, Wang JH, Goodell MA, Taegtmeyer H. Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart. Proc Natl Acad Sci U S A. 2016

2015 - 2010

  1. Aksentijević D, McAndrew DJ, Karlstädt A, Zervou S, Sebag-Montefiore L, Cross R, Douglas G, Regitz-Zagrosek V, Lopaschuk GD, Neubauer S, Lygate CA. Cardiac dysfunction and peri-weaning mortality in malonyl-coenzyme A decarboxylase (MCD) knockout mice as a consequence of restricting substrate plasticity. J Mol Cell Cardiol. 2014;75:76-87. PMID: 25066696; PMCID: PMC4169183. Article

  2. Karlstädt A, Fliegner D, Kararigas G, Ruderisch HS, Regitz-Zagrosek V, Holzhütter HG. CardioNet: a human metabolic network suited for the study of cardiomyocyte metabolism. BMC Syst Biol. 2012;6:114. PMID: 22929619; PMCID: PMC3568067. Article

  3. Gille C, Bölling C, Hoppe A, Bulik S, Hoffmann S, Hübner K, Karlstädt A, Ganeshan R, König M, Rother K, Weidlich M, Behre J, Holzhütter HG. HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Mol Syst Biol. 2010;6:411. PMID: 20823849; PMCID: PMC2964118. Article